Most Important Information About Cialis
Lilly and ICOS, the joint venture two big industrial pharmaceutical monsters is claiming to provide the most effective medication of erectile dysfunction and impotence in men. Their product under discussion is named Cialis, chemically it is mostly comprised of tadalafil. Not only do they claim to cure the disease but also to secure the integrity of other body mechanisms and prevent them from being influenced by the drug. Getting professional opinions, those claims seem to be true enough to consider this medication of impotence the only future remedy of the disease it cures or at least the only predecessor.
Unlike all other such medications, Cialis is highly specific of its function, dropping the characteristic of its stray actions on closely related metabolic systems of the body. PDE-5 inhibition is the only and main target of the drug for which it is designed. It doesn’t impacts or PDE systems thus reducing the spectrum of possible side effects. PDE-5 inhibition is followed by marked decrease in the rate of degradation of cGMP by this enzyme. cGMP is related to the production of NO from the vascular endothelial cells. With a sustained cGMP level, its concentration becomes increased and marked vasodilatation is observed in the areas where PDE-5 is found and inhibited by the drug. PDE-5 is highly specific enzyme found especially in lungs and penile tissues, when inhibited in penile tissues; it causes relaxation of the blood vessels which leads to increase n the room for the blood to enter the organ and fill it to change its posture from flaccid to erect due to the spongy nature of the corpora cavernosa of the penis which is the main blood filling organ of the male external genital. This leads to relief of the irresponsive genital. If the optimal effect of the drug is to be observed, appropriate sexual stimulation is the necessary evil because the drug is not capable of working independently due to its inhibiting nature and not the stimulating one. Though, it significantly magnifies the simulation once it is applied.
Cialis comes in three dosage forms of 5 mg, 10 mg and 20 mg tablets which are best recommended to be taken orally half an hour before engaging in sexual interaction. Do not administer the drug for more than once a day as it is a potent vasodilator, its over dosage may lead to life threatening hypotension. The drug is contraindicated in conditions when you have heart, liver and kidney diseases. It is highly restricted from co-administration with nitrate containing drugs.
There are certain peculiarities with this wonder drug. It is capable of providing effective time of up to 36 hours, which is more than enough to fully satisfy anyone’s sexual needs. Secondly, Cialis users could enjoy eating any sort of food stuff while on the drug, that is, it is food insensitive too. Thirdly, the drug is extremely safe as it doesn’t cause side effects which other members of the drug family threaten of. Possible side effects of the drug are headache, stomach ache, back ache, dizziness and problems related to nose which are supposed to go away within a couple of hours.
Application of this drug forces out impotence and depressed sexual activity of man of any age. And, proudly, our online pharmacy boasts of providing its customers the very same original quality medication at a single click and most significantly, in a highly affordable fashion.